Phd Candidate

: Discover personalized medical solutions for environmentally triggered diseases to promote a healthier society in a rapidly changing world.

At our institute you will find a scientifically stimulating international environment. Together with renowned scientists and supported by an excellent infrastructure you will have the opportunity to make an important contribution for a healthier society.

Lung transplantation is the last resort for patients with end-stage lung diseases. Unfortunately, lung transplantation displays the worst long-term survival in all solid organ transplantation. Here, we aim to elucidate the contribution of specific mechanisms of immunoferroptosis as the primary cell death in chronically rejecting lung allografts. The aim of this position is to define the contribution of ferroptosis to the development of lung allograft rejection after lung transplantation by using conditional knockout mice in an experimental model and in human samples during the clinical follow-up of lung transplanted patients.

We, the Institute of Lung Health and Immunity, are looking for a highly motivated

Full time

Neuherberg near Munich

PhD

Your mission
- Analysis of ferroptosis and immune cell markers in lungs from lung transplant models
- Validation of markers in human transbronchial biopsies, BALF and blood samples during the clinical follow-up of transplanted patients
- Ex vivo cell culture models of Immunoferoptosis
- Gene expression and analysis, flow cytometry, immunohistochemistry/fluorescence
- Project management (data analysis, quality assurance and monitoring, writing of reports and publications)

Your qualifications
- Master's degree in biology, immunology or related area
- Previous experience with cell culture techniques
- Previous flow cytometry experience
- Passion for science, innovation and creative and independent work
- Excellent communication and teamwork skills
- Excellent written and spoken English

**Desired qualifications**:

- Experience of single-cell genomics technologies a plus
- Previous experience in mouse work is considered a plus

What we offer you

scientific training at Graduate School
work-life balance
flexible working hours & time off in lieu
30 days annual leave
on-site health management service
career consultation
mobile work
on-site nursery
company pension scheme discounted public transport ticket
Munich, with its numerous lakes and its vicinity to the Alps, is considered to be one of the cities with the best quality of life worldwide. With its first-class universities and world-leading research institutions it offers an intellectually stimulating environment.

This position also provides the opportunity for you to build specialist knowledge and collect significant professional experience, both of which will help advance your scientific career.

Remuneration and social benefits are based on the collective wage agreement for public-sector employees at federal level (EG 13 50% TV EntgO Bund). In addition, there is also the possibility of granting an allowance if the necessary conditions are fulfilled. The position is (initially) limited to three years, but under certain circumstances an extension can be arranged.

If you have obtained a university degree abroad, we require further documents from you regarding the recognition of the degree.

Interested?
Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Institute of Lung Health and Immunity
Ingolstädter Landstraße 1

85764 Oberschleißheim