Bioinformatic Scientist, Referenz:

BIOINFORMATIC SCIENTIST (M/F/d) _
- in Cancer Genomics _
- Full time - Mainz_

We are looking for a new team member in our **Computational Medicine** unit to start as soon as possible. The

We aim to detect tumor-specific transcripts and splice junctions that encode potential neoantigen targets by

analyzing large-scale RNA sequencing data (short and long reads) from tumor and healthy samples in internal

and publicly available resources. In close collaboration with experimental teams, the detection pipelines and

individual targets will be confirmed on the level of transcript and peptide abundance as well as

immunogenicity.

The Computational Medicine unit is an interdisciplinary team of dedicated and enthusiastic scientists, software

developers, PhD students, and graduate students from diverse backgrounds, including computer science,

molecular biology, bioinformatics, and mathematics. We strongly collaborates with other units in TRON and

with external partners to develop software, predictive models, and data analysis for innovative

immunotherapies against cancer and other diseases.

**Your tasks and responsibilities**:

Analyzing large-scale short
- and long-read RNA-sequencing data

transcriptomes and predict tumor-specificity

Development of reproducible detection pipelines and data-driven prediction models

Defining short-lists of promissing targets for experimental confirmation

Designing and discussing long-read sequencing and further confirmation experiments

Present your work in meetings and at conferences, write reports and publish manuscripts

**What you bring: **

A completed PhD in bioinformatics, computational biology or related field

Demonstrated proficiency in analyzing sequencing data of large-scale cancer cohorts

Experience with long-read sequencing data for transcriptome characterization

Expertise in developing reproducible data analysis workflows in a HPC linux environment

Excellent data visualization and communication skills

Experience with data from proteomics, ligandomics or immunogenicity screening experiments would be

advantageous

Enthusiasm and curiosity for the diverse activities of our research institute as well as the ability to work in a

team completes your profile.
- PLATZHALTER ADMIN (M/F/D) _
- Vollzeit - Mainz _

**TRON** - Translational Oncology at the University Medical Center of the Johannes Gutenberg University Mainz non-profit GmbH

**We offer: **

A dynamic, innovative and creative research environment

An open, collegial and cordial working atmosphere in a respectful corporate culture

A high degree of diversity in the workforce

Flat hierarchies

Performance-related remuneration and other benefits

The opportunity for personalised further training

Good transport connections by public transport and car as well as bicycle parking spaces

The opportunity for hybrid working

academic research with the requirements of quality-controlled industrial developments. At TRON, we share a

common mission to develop innovative solutions for the immunotherapeutic treatment of cancer, infectious

diseases and other serious diseases with high medicinal need for development.

TRON was founded in Mainz in 2010 and works in close cooperation with universities and hospitals as well as

with regional, national and international research institutions and pharmaceutical companies.

As part of our team, you have the opportunity to be at the forefront of translational science with us.

If all this appeals to you, we look forward to getting to know you.

Job-ID: _51004-24-02-WAPRO_.

**TRON** - Translational Oncology at the University Medical Center of the Johannes Gutenberg University Mainz non-profit GmbH