(Senior) Research Associate

vor 7 Monaten


Planegg, Deutschland iOmx Therapeutics AG Vollzeit

**Your Tasks and Responsibilities**:

- You will strengthen our pre-clinical pharmacology & biomarker development team by contributing to the
- (pre-)clinical research and development of novel immune-checkpoint inhibitors and their further clinical development. Your tasks include:

- Design and implementation of cell-based assays to analyze the pharmacological impact of novel immune-checkpoint inhibitors on primary immune cells and tumor cells using various immunological and cell-based assays
- Detailed analysis of primary immune cell (lymphoid and myeloid) subsets, their activation and function using flow cytometry and other advanced immunological assays
- Design, implementation and qualification of _in vitro_ and _ex vivo_ cell-based and cell-free biomarker assays
- Perform routine culture and expansion of primary immune cells, tumor-infiltrating lymphocytes and tumor cell cultures
- Careful documentation as well as presentation of your results in internal meetings

**What we are looking for**:

- You hold a degree in biology, biotechnology or related fields, or have completed vocational training as a laboratory assistant such as BTA, MTA, CTA or equivalent with 2+ years of industry experience
- Deep knowledge of tumor biology and immunology is advantageous
- You have hands-on experience in immune cell (lymphoid and myeloid) functional assays (cytotoxicity assays, cytokine analysis, polarization assays, mixed lymphoid reaction assays, etc.)
- You are experienced in cell biology (isolation and cultivation of primary cells and cell lines, proliferation assays) and immunological techniques, e.g., ELISA, bead-based multiplex assays, multicolor flow cytometry (> 8 colors) including independent panel design, western blot, etc.
- Molecular biology assays, such as DNA transfections and transduction are familiar to you
- You are proficient with MS Office, GraphPad Prism and FlowJo
- Experience in scientific data analysis and visualization, e.g., tSNE, PCA, heatmaps, would be a plus
- You are fluent in English (spoken and written)
- You are a highly motivated, flexible, and creative individual with excellent communication and interpersonal skills
- You are efficient at working in collaborative and diverse teams

**Why to join iOmx?**:

- We are a young biotechnology company with about 50 employees in Martinsried/Munich. We are working in flat hierarchies with short decision-making processes and offer a rewarding career in a welcoming, trusting and international work environment.
- By joining us you can expect the following:
- Opportunity for personal development
- Growth-oriented and innovation-driven company culture
- 30 days paid vacation
- Flexible working time and much more

**About us**:

- i_
- Omx Therapeutics is a clinical-stage company in the field of immuno-oncology located in Martinsried/Munich, Germany._
- We are focusing on the development of first-in-class cancer immunotherapies, addressing novel immune evasion biologies, which are hijacked by tumors and their microenvironment._
- We are looking for highly motivated, self-driven and competent colleagues who share our vision and wish to contribute to translating this vision into reality._



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