Phd Candidate

We are announcing a 65% position as

**Antimicrobial Compounds for Inflammation Control**

in the Priority Area Infection at the Research Center Borstel. The position is offered for 3 years.

The Research Center Borstel (RCB) is an internationally operating Lung Center within the Leibniz Association, financed by the

Federal Government and the State of Schleswig-Holstein. Our central task is basic and translational research in the field of

respiratory diseases. We operate extensive laboratory and research infrastructures. Academically, we are closely linked with

neighboring universities (Lübeck, Kiel) and clinically with the University Hospital Schleswig-Holstein. Our goal is to improve existing methods for the detection, prevention and treatment of lung diseases and to develop new, innovative therapeutic approaches.

**JOB DESCRIPTION**

Endotoxin-mediated hyper-inflammation is a key factor in the pathogenesis of many diseases, such as severe pneumonia and bacterial sepsis. This aspect has hardly been taken into account in the development of new antibiotics. In the project you will investigate the mode of action of endotoxin-neutralizing agents on immune cells. Combining methods from membrane biophysics, structural biology and immunology, you will establish the mode of action of peptide-mediated endotoxin neutralization and demonstrate the immunological effect in medically relevant systems such as human macrophages and donor blood. Your work will thus contribute to the development of new agents for the treatment of infections and inflammatory diseases.

**YOUR QUALIFICATION**
- Master's degree in life sciences, biology, biophysics, or related field
- Practical experience in cell biology, immunological, or biophysical methods
- Curiosity about interdisciplinary work and commitment to work in a team
- Excellent communication skills and good command of English

**OUR OFFER**
- A self-responsible workspace in a motivated team
- The possibility to use state-of the art methods of single-cell analysis
- Personal atmosphere and support
- A structured and certified PhD training Program in the „Borstel Biomedical Research School“
- Your new workplace is located in a top class research center close to Hamburg
- Payment according to TVöD-VKA incl. all benefits usually offered in the public sector
- Family-friendly working condition, Childcare Centre, flexible working hours, and workplace health promotion

Art der Stelle: Teilzeit, Befristeter Vertrag
Vertragsdauer: 36 Monate
Arbeitsstunden: 25,35 pro Woche

Arbeitszeiten:

- Montag bis Freitag

Leistungen:

- Betriebliche Weiterbildung
- Flexible Arbeitszeiten
- Homeoffice
- Sprachkenntnisse werden vermittelt

Sprache:

- Englisch (Wünschenswert)
- Deutsch (Wünschenswert)

Arbeitsort: Vor Ort

Bewerbungsfrist: 07.07.2023