Postdoc Position

20.02.2023

**Postdoc position (E13) at the Leibniz Institute for Immunotherapy (LIT) with flexible starting date (M/F/d)**:
**Leibniz-Institut für Immuntherapie (LIT), Regensburg**:
Postdoc position (E13) at the Leibniz Institute for Immunotherapy (LIT) with flexible starting date (M/F/d)

**About the project**

Our group investigates the principles of gene-regulation in functional and dysfunctional immune cell populations in cancer (Riegel et al. 2023 Molecular Cell). In this project that is supported by the “Deutsche Krebshilfe” (“German Cancer Aid”), we aim to improve chimeric antigen receptor (CAR) T cell therapies by targeting genes and gene-regulatory processes to prevent CAR T cell dysfunction. Your tasks include
- CAR T cell design and manufacturing
- Use and further develop CRISPR (epi-)genome editing methods in CAR T cells
- Using cellular (e.g., FACS) and molecular (e.g., single cell analysis, next generation sequencing) methods to characterize cell therapy products
- Test the function of CAR T cells in vitro and in in vivo murine disease models

**Requirements**:
We are looking for a highly motivated scientist who is enthusiastic to work in a young and ambitious team on a competitive project, and who fits the following profile:

- PhD in molecular biology/biochemistry/molecular medicine or related fields
- Creative mind that is eager to shape the project and who wants to make an impact on biomedical research
- Experimental training in molecular cell biology and immunology
- Excellent oral and written communication skills and team spirit
- Experience in genome editing, mouse models (FELASA certificate), and next generation sequencing methods advantageous but not absolutely required
- Strong interest in immunology & cancer

**The Schmidl lab**

We offer the opportunity to work at the interface of immunology and cancer, which is one of the most exciting fields of recent biomedical research. We provide a dynamic and motivating working environment with flat hierarchies where you can foster your skills and get the opportunity to use top-notch technologies. The small lab size offers excellent mentoring and the opportunity to contribute and develop own ideas. We closely collaborate with experts in cancer immunotherapy and CAR T cells on this project to provide you with the possible support.

The remuneration is based on TV-L.

Moreover, the LIT advocates for the compatibility of family and career.

Please note that expenses that may arise in the context of an eventual job interview cannot be reimbursed.

Application deadline is March 26th, 2023.