Polymer Membranes for The Incorporation of Nanopores

vor 2 Wochen

Freiburg, Deutschland Albert-Ludwigs-Universität Freiburg Vollzeit

**Polymer membranes for the incorporation of nanopores**:

- Réf
- **ABG-110266**
- Sujet de Thèse- 16/01/2023- Contrat doctoral- Albert-Ludwigs-Universität Freiburg- Lieu de travail- Freiburg im Breisgau - Allemagne- Intitulé du sujet- Polymer membranes for the incorporation of nanopores- Champs scientifiques- Physique
- Chimie

**Description du sujet**:
**Project description**

In the framework of the interdisciplinary cluster Nanodiag, the Polymer Physics group will investigate and optimize such model membranes built from block copolymers or lipo-polymers for an innovative nanopore technology.

Biological nanopores can be produced from pore-forming proteins which insert into a lipid membrane and organise themselves to create a nanometre-sized channel across the membrane. These nanopores allow transport of ions and (bio)-molecules through the membrane. In biological systems, such nanopore channels regulate the transport of ions and molecules in and out of cells.

Embedded in the electrically insulating membrane, which is suspended in aqueous solution, such a nanopore can be employed as a single molecule detector which even can discriminate between different species. When voltage is applied across such a detector-membrane, a current of ions flows through the pore. The lengths and diameters of biological pores are commensurate with molecular dimensions and therefore the ionic current is blocked when a molecule is translocating through the pore. Both the duration of the blockade and the value of the residual current provide information about the interaction between the translocating species and the pore and can therefore be used to identify individual molecules.

**Nature du financement**:

- Contrat doctoral**Précisions sur le financement**:
**Présentation établissement et labo d'accueil**:

- Albert-Ludwigs-Universität FreiburgThe Polymer Physics group in Freiburg, headed by Professor Günter Reiter, has a long-standing expertise in preparation, visualisation and analysis of properties and molecular structures of ultrathin polymer films, in particular by means of atomic force microscopy at the nanometre scale. In this context, preparation of films of surface-active molecules which assemble as a monolayer at the water surface of a Langmuir trough allows to obtain almost two-dimensional monolayers in a controlled and tuneable manner.

**Site web**:
**Intitulé du doctorat**:

- Dr. rer. nat.**Pays d'obtention du doctorat**:

- AllemagneWe are looking for a highly motivated PhD student who has a master degree in physics, chemistry, nanoscience or another related field. Experimental skills and a solid background in physics or chemistry of macromolecules are required. However, even more important is the capability to work in a multidisciplinary research team and to acquire all relevant competencies which are needed to solve underlying physical and chemical problems related to achieving suitable membrane systems for an innovative nanopore technology.

We offer an exciting field of multidisciplinary research of societal relevance, advanced and unique experimental tools as well as intensive supervision, embedded in a dynamic international team. The Experimental Polymer Physics group provides its infrastructure and know-how for the work on the PhD project.- 15/02/2023

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