PhD student

PhD student (f/m/d) Clinic for Gastroenterology, gastrointestinal Oncology and Endocrinology The Clinic for Gastroenterology, gastrointestinal Oncology and Endocrinology of the University Medical Center Göttingen is looking for PhD student (f/m/d) 3-year doctoral program, part-time (25,025 h/week) | salary according to TV-L The University Medical Center Göttingen is a tertiary care center and offers great development potential. Its 7,900 employees work in over 65 departments and facilities to provide top-quality patient care, excellent research and modern teaching. Göttingen, “City of Science-, located near the center of Germany, the University Medical Center Göttingen is embedded in the city-s attractive network of scientific research facilities. The Ellenrieder Lab has a longstanding expertise in basic and translational cancer research with a particular focus on pancreatic cancer. Specifically, we are interested in signaling, transcriptional and metabolic pathways involved in the regulation of tumor growth, plasticity and chemoresistance. Thereby, we are addressing different regulatory mechanisms of genome / chromatin dynamics as well as metabolic changes and their relevance in pancreatic cancer progression and resistance. Our group is a part of the clinical research unit (CRU) 5002 “Deciphering Genome Dynamics for Subtype-specific Therapy in Pancreatic Cancer-, and within the CRU we are characterizing novel molecular vulnerabilities and their potential for tailored treatment approaches. Hereby, we use different in vitro and in vivo tumor models and extensive genome wide and bioinformatic approaches for transcriptional, translational and metabolic characterization. In the context of the CRU, we are especially working with molecular and genomic characterized patient derived xenografts, organoids and cells lines. You will work in an international group, in strong interaction with different cooperation partners within the department and multiple cooperation partners within the clinical and basic research environment of the university. The project includes standard molecular biology techniques, NGS-sequencing as well as metabolic plasticity analysis. The regular participation and presentation of results in the Department and G-CCC (Göttingen-Comprehensive Cancer Center) seminars are part of the work. Further, the student has the chance of joining a diversity of courses (lab techniques, soft skills) and yearly retreats, offered by the PhD program and the CRU. Your responsibilities: plan and conduct projects within the scope of metabolic and stress adaptation in pancreatic cancer writing manuscripts for publication guide and train undergrad and medial students in the lab Your profile: masters degree in Molecular Biology, Molecular Medicine or a related expertise in cell culture, molecular biology, sequencing and NGS approaches experience with one or more of the following fields is a plus: pancreatic cancer, NGS data analysis, Calcium signaling, UPR, metabolism fluency in English is mandatory, German skills are beneficial high self-motivation, interested in the interaction and collaboration between physicians and scientists the participation in a PhD program of the GGNB (e.g. Molecular Medicine) is mandatory and you should fulfill the requirements for joining the program ( Our offer: a PhD position for 3 years joining a lively lab with strong interactions in the department strong network and close interactions within the CRU 5002 and the Göttingen Research Campus salary according to the TV-L including social benefits Please hand in the following documents as a single pdf (Motivation letter, CV, University certificates, Publication record, at least two references). The University Medical Center Göttingen takes flexible account of the individual design of working hours at the workplace. It is interested in implementing the wishes of its employees as far as possible. If you are interested in this job and have specific questions about working hours, please contact us. The University Medical Center Göttingen is committed to professional equality. We therefore seek to increase the proportion of under-represented genders. Applicants with disabilities and equal qualifications will be given preferential treatment. We look forward to receiving your application by 05/31/2024 University Medical Center Göttingen Clinic for Gastroenterology, gastrointestinal Oncology and Endocrinology Prof. Dr. V. Ellenrieder Göttingen Phone: E-Mail: Travel and application fees cannot be refunded or transferred. Please send your application only via e-mail as a PDF-file.