PhD student
vor 3 Wochen
Heinrich-Heine-Universität Düsseldorf - Logo
At the Institute of Microbiology ( ) of the Heinrich Heine University Düsseldorf a position as a PhD student (m/f/d) in RNA biology in infection is to be filled
PhD student (m/f/d) in RNA biology in infection
Job-ID: J000000409
Start date: earliest possible date
Location: Düsseldorf
Working hours: Part time
Schedule: 65 %
Job Category: Research and Development
Organization: Mathematisch-Naturwissenschaftliche Fakultät
Payment group: EGr. 13 TV-L
Apply till: 21.03.2025
The Institute of Microbiology is part of the Faculty of Mathematics and Natural Sciences HHUD, and follows three pillars of research and education: 1. Microbial RNA biology 2. Microbial Interaction and 3. Microbial Biotechnology. Therefore, we cover broad research interest for optimal training and development of PhD students. We do have ample experience in graduate education including soft skill courses like «good scientific practise», «project coordination» and «scientific writing».
Main tasks
Fungal pathogens pose serious threats to public health and agriculture. They can even be responsible for the extinction of species, thereby shaping whole ecosystems. For their defeat, it is vital to uncover their infection strategies. Thereby, their Achilles' heel can be identified for the development of novel fungicides. We investigate the role of RNA-binding proteins during pathogenic development of the plant pathogenic fungus Ustilago maydis (Sankaranarayanan 2023, PloS Path). We discovered that the multi-KH domain protein Khd4 is essential for infection. This RNA-binding protein regulates the stability of target mRNAs that function during regulation of intracellular membrane trafficking (Sankaranarayanan 2023, PNAS). The aim of this project is to understand the underlying molecular mechanisms. To this end we combine RNA biochemistry with microbial genetics and live cell observation. In particular, we aim to use innovative RNA proximity labelling approaches to understand regulation at the transcriptome-wide level. S. Sankaranarayanan$, S. Kwon$, K. Heimel, M. Feldbrügge (2023) The RNA world of fungal pathogens. PLoS Path, 30: e1011762. S. Sankaranarayanan, C. Haag, P. Petzsch, K. Köhrer, A. Matuszynska, K. Zarnack, M. Feldbrügge (2023) The mRNA stability factor Khd4 defines a specific mRNA regulon for membrane trafficking in the pathogen Ustilago maydis. Proc Natl Acad Sci. 120: e2301731120.
Your profil
A Master degree in biology/biochemistry or related life sciences
Practical experience in molecular biology, biochemistry and/or microbiology
Experience in eukaryotic microorganisms, plant pathogens, RNA biochemistry and/or fluorescence microscopy is desirable
A strong motivation in experimental work, literature search and scientific writing
Excellent communication skills in written and spoken English and in communicating in an interdisciplinary research environment
Participation in teaching of microbiological courses is expected
Our Offer
The employment is initially limited for a period of one year with an option for prolongation. It is a qualification position in the sense of the Act of Academic Fixed-Term Contract (Wissenschaftsvertragsgesetz - WissZeitVG), which is to promote the scientific qualification of the employee.
We offer an excellent research environment with state of the art reseach equipment and the opportunity to integrate into our research networks such as the Collaborative Research Centre SFB1535 "Microbial Networking", the Cluster of Excellence CEPLAS «Smart Plants», and the Graduate School "Molecules of Infection". The pay grade is 13 TV-L 65%.
Our benefits
Company pension grant
Flexitime
International work
Traveling
Union rates
Free parking
Good transport connection
Heinrich Heine University upholds the principle of "Excellence through Diversity". It has signed the "Diversity Charter" and successfully participated in the Stifterverband's audit "Shaping Diversity". It is certified as a family-friendly university and has set itself the goal of promoting diversity among its staff. Applications from people of all genders are expressly welcome. Applications from women will be given preferential consideration in accordance with the State Equal Opportunities Act. The application of severely disabled persons and persons with equivalent disabilities is also welcome. In order for a severe disability or equality to be taken into account, please provide evidence of this with suitable documents.
Contact
Carola Leitsch, 0211/81-14720
Apply online now
Heinrich-Heine-Universität Düsseldorf
Dezernat Personal
hhu.de
-
PhD student
Vor 6 Tagen
Köln, Nordrhein-Westfalen, Deutschland Uniklinik Köln Vollzeit» Your tasks You will work in an interdisciplinary team of basic researchers, computational biologists and environmental and biomedical scientists to improve our understanding of the impact of chemical agents on our and environmental health as part of the large Project. Specifically your tasks will be: Working closely with scientists all over...
-
PhD student position
Vor 6 Tagen
Köln, Nordrhein-Westfalen, Deutschland Uniklinik Köln Vollzeit» Your tasks The DFG-funded Collaborative Research Centre (CRC1218) "Mitochondrial regulation of cellular function" , Department of Dermatology at the University of Cologne is seeking applications for one PhD student position (f/m/x) to be employed under a limited-time contract of 3 years (third-party funded). We are searching for...
-
PhD Student
Vor 6 Tagen
Köln, Nordrhein-Westfalen, Deutschland Uniklinik Köln Vollzeit» Your tasks Use cell lines and mouse models to investigate the causal link between mitochondrial dysfunction and the pathophysiology of cancer. Use molecular biology, biochemistry, and computational techniques to investigate metabolism at the molecular level. Perform multi-omics analyses (metabolic, proteomic and transcriptomic studies) and...
-
Köln, Nordrhein-Westfalen, Deutschland Uniklinik Köln Vollzeit» Ihre Aufgaben Aktive Unterstützung von und Beteiligung an laufenden, mit öffentlichen Mitteln finanzierten Forschungsprojekten Erforschung und Entwicklung von Medikamenten für die Reparatur des geschädigten Nervensystems Betreuung von Bachelor-, Master- und PhD-Student/innen Labormanagement einschließlich Biosicherheit (gemeinsame...
-
Servicetechniker Funk-
Vor 6 Tagen
Köln, Nordrhein-Westfalen, Deutschland Rohde & Schwarz VollzeitMake ideas real - with the perfect job. Right now we have several job openings for you. Functional area All Administration 9 Application Development 26 Construction 7 Controlling 2 Cybersecurity 2 Finance 14 Hardware Development 37 Human Resources 14 Information Technology 43 Law 5 Manufacturing 25 ...
-
Postdoc in cellular immunology and metabolism
vor 2 Wochen
Köln, Nordrhein-Westfalen, Deutschland Rheinische Friedrich-Wilhelms-Universität Bonn VollzeitThe group of Prof. Dr. Sven Burgdorf at the lab of Cellular Immunology of the LIMES Institute is looking to fill the following position as soon as possible, full time and on a fixed-term contract for 3.5 years: Postdoc in cellular immunology and metabolism The Life & Medical Sciences (LIMES) Institute is an interdisciplinary institute for basic biomedical...
-
Vertriebsassistenz (m/w/d)
Vor 6 Tagen
Köln, Nordrhein-Westfalen, Deutschland Rohde & Schwarz VollzeitMake ideas real - with the perfect job. Right now we have several job openings for you. Functional area All Administration 7 Application Development 31 Construction 6 Controlling 7 Cybersecurity 3 Finance 13 Hardware Development 37 Human Resources 11 Information Technology 37 Law 2 Manufacturing 24 ...
-
Vertriebsleiter (m/w/d) – IT Security Sales
Vor 6 Tagen
Köln, Nordrhein-Westfalen, Deutschland Rohde & Schwarz VollzeitMake ideas real - with the perfect job. Right now we have several job openings for you. Functional area All Administration 8 Application Development 31 Construction 6 Controlling 8 Cybersecurity 2 Finance 18 Hardware Development 42 Human Resources 10 Information Technology 42 Law 4 Manufacturing 26 ...
-
Phd Student Position
Vor 4 Tagen
Köln, Deutschland Universitätsklinikum Köln VollzeitWe are looking to support our rapidly growing team as soon as possible: **PhD Student position (f/m/x)**: **Herzchirurgie** - TV-L: 25 h/week (64,94%) initially limited for 1 year according to WissZeitVG, extension optional Your salary will be based on TV-L - TV-L: 25 h/week (64,94%) initially limited for 1 year according to WissZeitVG, extension...
-
Phd Student
Vor 4 Tagen
Köln, Deutschland Universität zu Köln VollzeitWe are one of the largest and oldest universities in Europe and one of the most important employers in our region. make us attractive for students and researchers from around the world. We offer a wide range of career opportunities in science, technology, and administration. The Bollenbach group at the Institute for Biological Physics investigates evolution...
-
Phd Student
Vor 4 Tagen
Köln, Deutschland Universitätsklinikum Köln VollzeitZur Unterstützung unseres stark wachsenden Teams suchen wir zum nächstmöglichen Zeitpunkt: **PhD student (w/m/d) auf dem Gebiet der Hämato-Onkologie**: **AG Pflug/Braun**, Klinik I für Innere Medizin** - TV-L 25 Std./Woche befristet bis zum 30. April 2028 im Rahmen eines Drittmittelprojektes Vergütung nach TV-L - TV-L 25 Std./Woche befristet bis zum...
-
Phd Student
Vor 4 Tagen
Köln, Deutschland Universitätsklinikum Köln VollzeitWe are looking to support our rapidly growing team as soon as possible: **PhD student (f/m/x) in hemato-oncology**: **Pflug/Braun lab,** Clinic I for Internal Medicine** - TV-L: 25 h/week (64,94%) limited until 30. april 2028 according to WissZeitVG within the framework of a thirdparty funded project Your salary will be based on TV-L - TV-L: 25 h/week...
-
Phd Student
Vor 4 Tagen
Köln, Deutschland Universität zu Köln Vollzeit**PhD student / postdoc in biological physics & systems biology(f/m/x)**: **Institute for Biological Physics**: The Bollenbach group at the Institute for Biological Physics investigates evolution and interactions in microbial systems, especially in the context of antibiotic resistance and polymicrobial consortia. The group combines methods from molecular and...
-
Phd Position
Vor 4 Tagen
Köln, Deutschland Universität zu Köln VollzeitWe are one of the largest and oldest universities in Europe and one of the most important employers in our region. make us attractive for students and researchers from around the world. We offer a wide range of career opportunities in science, technology, and administration. Bacteria are unicellular organisms, yet they can form structured communities called...
-
Phd Candidate and Research Assistant
Vor 5 Tagen
Köln, Deutschland Universität zu Köln VollzeitWe are one of the largest and oldest universities in Europe and one of the most important employers in our region. make us attractive for students and researchers from around the world. We offer a wide range of career opportunities in science, technology, and administration. The Chair of Entrepreneurship and Management has a vacancy for a full-time research...
-
Doctoral Student
Vor 5 Tagen
Köln, Deutschland Universität zu Köln Vollzeit**Faculty of Management, Economics and Social Sciences** **Doctoral Student / Research Assistant in Behavioral Economics(f/m/x)** **Department Corporate Development**: - The Department of Coporate Development focuses in its research and teaching on the management, strategy and design of organizations. Central areas of the department are entrepreneurship,...
-
Phd Student
Vor 4 Tagen
Köln, Deutschland Uniklinik Köln Vollzeit**Ihre Aufgaben**: Unsere Gruppe sucht derzeit eine hochmotivierte und qualifizierte Person mit einem Hintergrund in Life Sciences. Im Rahmen des Promotionsprojektes wird der pathogenetische Einfluss des Tumormikromilieus in T-Zell - Lymphomen untersucht. Im Rahmen dieses Projekts verfolgen wir das Ziel, eine umfassende multi-omische Charakterisierung des...
-
Doctoral Position
Vor 4 Tagen
Köln, Deutschland Universität zu Köln VollzeitWe are one of the largest and oldest universities in Europe and one of the most important employers in our region. make us attractive for students and researchers from around the world. We offer a wide range of career opportunities in science, technology, and administration. - ing how microbes alter specific metabolic and signalling pathways in host cells to...
-
Postdoc (F/m/x) Neuroinflammation in Tauopathies
Vor 4 Tagen
Köln, Deutschland Universitätsklinikum Köln VollzeitWe are looking to support our rapidly growing team as soon as possible: **Postdoc (f/m/x) Neuroinflammation in tauopathies**: **CECAD-CelluarStress Responses in Aging -Associated Diseases** - TV-L: 38,5 h/week (100%) initially limited for 3 years according to WissZeitVG Drittmittel Your salary will be based on TV-L - TV-L: 38,5 h/week (100%) initially...
-
Postdoctoral Researcher in Economic History
Vor 4 Tagen
Köln, Deutschland Universität zu Köln VollzeitWe are one of the largest and oldest universities in Europe and one of the most important employers in our region. make us attractive for students and researchers from around the world. We offer a wide range of career opportunities in science, technology, and administration. The position is based in the Department of Economics within the Faculty of...
-
Postdoc in Gene Edited Immunotherapies
Vor 2 Tagen
Köln, Deutschland Universitätsklinikum Köln VollzeitWe are looking to support our rapidly growing team as soon as possible: **PostDoc in gene edited immunotherapies (f/m/x)**: **Institute for Translational Immune-Oncology** - TV-L: 38,5 h/week (100%) initially limited until December 31, 2026 Your salary will be based on TV-L - TV-L: 38,5 h/week (100%) initially limited until December 31, 2026 Your salary...
